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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

SRAM Red AXS Caliper (single or pair)SRAM Red First Generation OG-1090 10 speed 11-23 CassetteSRAM Red Yaw 2x10 Speed Alloy Hidden Bolt Chainring 110mm BCD - 50tSRAM Rise 60 29 Front Wheel 15x110mm Boost, Carbon Rim Tubeless Compatible B1Sram Rival 22 - Road Bike Dual Pivot Brake CalipersSRAM Achse Maxle Stealth MTB Front Boost 12x100 mm

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By Connor Emdin
September 26, 2018

SRAM Rival BB30 22 Yaw Crankset 46-36T BCD 110 mm, 175 mm Cranks, 11-speed NEWSRAM Rival22 Bb30 10 Speed Cranks 36 52T 172.5mmSRAM Roam 50 Carbon 29 Rear Boost 12X148B WheelSram S600 Kettenschloss 3 x 8-fach Riegel 42-32-22t - 175 Mm, blueeblack - Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Sram Brake Lever Road S900 Carbon Lh - 00.5215.025.010 Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

SRAM X0 X.0 Rear Derailleur 10s Carbon Long CageSRAM X1 11-Speed Trigger ShifterSram x7 grip shift shifter new in the boxSram XG1150 11 Speed Cassette 10-42 SRAM CERAMIC BEARING AeroGlide PULLEYS fit RED Rear DERAILLEUR Replace FREE SHIP

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Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

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By Connor Emdin
June 27, 2018

SRAM X-Sync 2 Eagle Direct Mount Chainring 32T - BRAND NEWSRAM X-SYNC CHAINRING, 44T, 11 SPEED, 110 BCD, BRAND NEW IN BOXSRAM XX and 2008+ X0 9 10-Speed Derailleur Pulley Kit Does Not Fit Type 2 orSRAM XX1 Eagle Hollow Pin gold Kette chain SRAM crankset nx 1x11v gxp 175mm 32t black bike mtb

Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

SRAM Ersatz Für Schaltwerk X0 Type 2, Spann- und Leitrollen Set X0 Type 2

By Martina McGrath, MD
June 5, 2018

SRAM Avid T25 redor Bolt Kit, Titanium, Set of 6St. Croix 10th Anniversary Presentation Model 9200 APM 8' Fly Fishing Rod SRAM EX1 X-HORIZON™ Rear Derailleur 1X8 Speed

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Stamina Ab Hyper Bench Pro Abs Roller Home Gym Fitness Weight Equipment Exercise

By Lea Borgi, MD
May 16, 2018

Standard 1 Threaded EZ Curl Bar Standard Sporting GoodsStans Flow EX 26 Shimano XT M756 hub, DT Swiss, Mountain Bike Wheel Set. MTBStan's NoTubes 3.30 XD Driver Kit for 142mm Thru Axle Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”