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Do Large Clinical Trials Adequately Consider Individual Patient Physiology? Debating The RELIEF Study

By Michael Keane, BMBS, FANZCA and Shashikanth Manikappa, MD, DNB, FANZCA
February 21, 2019

Patient safety requires a well-informed debate about the rationale of large, randomized controlled trials (RCTs) and whether, by their very nature, they can adequately consider the unique physiology of every individual patient. 

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WAKE-UP Time for Thrombolysis in Acute Stroke?

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By Martina McGrath, MD
October 30, 2018

MRI thrombolysis for stroke of unknown time of onset

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Prior studies have suggested a particular pattern may be seen on an MRI of the brain in the early hours following stroke onset; a visible ischemic lesion on diffusion-weighted imaging along with the lack of a hyperintense signal in the same area on fluid-attenuated inversion recovery (FLAIR). The benefit of aggressive stroke intervention in patients with the combination of unknown time of symptom onset and this particular signal mismatch on MRI brain scans is unknown. Continue reading “WAKE-UP Time for Thrombolysis in Acute Stroke?”

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By Olivier Lucar
October 16, 2018

Mavic Crossmax SLR 650b Lefty Crossmax ST29 Lefty (2014) M40771, M40076Mavic CXP23 Rear Wheel Shimano Dura-Ace FH-7800 Hub (W50)MAVIC GP 4 tubular rims Schlauchreifenfelgenpaar 5Mavic Ksyrium ES Anniversary rear hub 20h 130mm + Mavic skewerMAVIC MA40 rims 28' 700c 36h CLINCHER VGCMalino Judo Gi Suit Adult Uniform with Free Belt Cotton 450g White Size 5 180

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By Connor Emdin
September 26, 2018

Mavic Open Sport Road Bike Wheelset Wheels Hub fits CAMPAGNOLO 9 10 11 SpeedMavic skewers, pair front and rear. Road and MTB. NIBMavic XC717 Mountain Wheels 26x1.5 Shimano M678 CL Disc Hubs 8-10 SpeedMax Trousers Running Pluto blueee Colour orange Zipper behind gangs Reflective Continue reading “Use of Guideline-Recommended Medical Therapy in Patients with Heart Failure”

Restrictive versus Liberal Fluid Therapy in Abdominal Surgery

By Connor Emdin
August 28, 2018

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Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?

By Martina McGrath, MD
August 8, 2018

It is estimated that 1 in every 7.5 people in the US will die of sudden cardiac death.Mando de cambio SRAM GX Grip Shift 2v Delantero Survival following out-of-hospital cardiac arrest has increased in recent years, from 10.2% in 2006, to 12.4% in 2015.1 However, only 9% of those surviving to hospital discharge were classified as having good functional status. Therefore, significant long-term neurologic impairment is a common outcome of cardiac arrest. Continue reading “Epinephrine in Out-Of-Hospital Cardiac Arrest: Increased Survival but at What Cost?”

Cervical Cancer Screening Using HPV Testing Alone: Are We There Yet?

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By Martina McGrath, MD
July 18, 2018

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Lumintrail USB Rechargeable LED Bike Light with Tail Light and Secure 800 Lumen nfnthv2026-Lights & Reflectors

Item specifics

New: A brand-new, unused, unopened, undamaged item in its original packaging (where packaging is ... Read moreabout the condition


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Bulb Type: LED EAN:






Number of LEDs: 3

Dulaglutide in Type 2 Diabetes: Do GLP-1 agonists delay progression of diabetic nephropathy?

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By Connor Emdin
June 27, 2018

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Procalcitonin-Guided Antibiotic Therapy in Lower Respiratory Tract Infection: Is It Safe?

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By Martina McGrath, MD
June 5, 2018

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Maxxis Ikon+ 3C EXO TR Tire Max Ikon+ 27.5x2.8 Bk Fold 120 3c xo tr

By Lea Borgi, MD
May 16, 2018

Maxxis Minion DHF 27.5x2.30 (650B) DD 3C Tubeless Ready Folding MTB Bike TyreMaxxis Minion DHF Front 3CGrip EXO TR Tire 27.5x2.5 Bk Fold 60 3cgrip exo tr wtMaxxis Minion DHF WT 3C DD TR Mountain Bike Tire 27.5x2.5 Continue reading “Does Menu Labeling Lead to Healthier Food Choices?”